A prospective analysis of viral immune escape in the chronic phase of the subtype C HIV-1 infections of India
نویسندگان
چکیده
Background HIV-1 is capable of evading CTL immune response through mutations in residues both within the epitopes and in sequences flanking the epitopes leading to viral diversity a major obstacle for vaccine design. The present study aims at identifying the HLA-restricted CTL escape mutations primarily in the asymptomatic phase, and examining a correlation between such mutations and disease progression.
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